Anaesthetic Management of Women With Heart Disease For Labor and Delivery

Condition(s): Heart Diseases Pregnancy
NCTId: NCT00403871

Official Title

Anaesthetic Management of Women With Heart Disease For Labor and Delivery

Summary

Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients. The period of greatest risk is peripartum while these patients are under the care of the obstetrician and anesthesiologist. We will evaluate the anesthetic management of all women with heart disease whose pregnancies were followed at the University Health Network and/or Mount Sinai Hospital between 1986 and 2001.

Detailed Description

Heart disease among pregnant women is increasing in incidence. The cardiovascular changes associated with pregnancy may be particularly hazardous for both mother and fetus in a subset of these patients. The period of greatest risk is peripartum while these patients are under the care of the obstetrician and anesthesiologist. Exposing a compromised patient to general anesthesia is further complicated by the cardiovascular stress response to intubation and surgery, the cardiorespiratory implications of mechanical ventilation, the cardiac depression and vasodilation from general anesthetics, residual post-operative respiratory depression from general anesthetics and narcotics and the stress of weaning from mechanical ventilation and post-operative pain.

In the Adult Congenital Heart Program, obstetric patients are followed the by a specialized team of cardiologists, obstetricians and anesthesiologists who also follow all pregnant women referred with acquired cardiac disease. From this referral practice approximately 100 patients per year are now followed during their pregnancy and delivery. In conjunction with the ongoing system we intend to identify all parturients who delivered at the University Health Network (Toronto General Hospital) or Mount Sinai Hospital between the years 1986 and 2001. We will evaluate the anesthetic management of all women with heart disease whose pregnancies were followed at the University Health Network and/or Mount Sinai Hospital between 1986 and 2001.

Eligibility

Eligibility Criteria

Gender Minimum Age Maximum Age Healthy Volunteers?
Female N/A N/A False

Inclusion Criteria:

- Pregnant women with congenital or acquired heart disease

- Pregnant women with arrhythmias are also included providing they had had symptomatic tachyarrhythmias or bradyarrhythmias requiring treatment

Exclusion Criteria:

- Women with isolated mitral valve prolapse including those with mild to moderated mitral regurgitation

- Women referred for termination of pregnancy

Interventions & Outcomes

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Facility Locations

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Clinical Research Study Facility Locations

Univeristy Health Network
Toronto, Ontario M5G 1Z5 Canada

Mount Sinai Hospital
Toronto, Ontario M5G 1X5 Canada

Related Keywords & Studies

Conditions and Diseases with Related Research Studies

  1. Heart Diseases
  2. Pregnancy

Related Intervention Keywords

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